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Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus.

The kinetic behavior of ribozymes derived from two types of multiple-ribozyme expression vector were examined. In some cases, multiple ribozymes were expressed as a single RNA molecule and all the ribozymes were simply connected in tandem (connected type). In other cases, multiple ribozymes were fla...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Ohkawa, J, Yuyama, N, Takebe, Y, Nishikawa, S, Taira, K
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47970/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11302
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