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DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2.

Integration of retroviral DNA into the host chromosome requires the integrase protein (IN). We overexpressed the IN proteins of human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) in E. coli and purified them. Both proteins were found to specifically cut two nucleotides off the ends of li...

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Autors principals: van Gent, D C, Elgersma, Y, Bolk, M W, Vink, C, Plasterk, R H
Format: Artigo
Idioma:Inglês
Publicat: 1991
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC328469/
https://ncbi.nlm.nih.gov/pubmed/1861975
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