DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2.

Integration of retroviral DNA into the host chromosome requires the integrase protein (IN). We overexpressed the IN proteins of human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) in E. coli and purified them. Both proteins were found to specifically cut two nucleotides off the ends of li...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	van Gent, D C, Elgersma, Y, Bolk, M W, Vink, C, Plasterk, R H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1991
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1861975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.14.3821
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