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Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay

BACKGROUND: This study assessed the Granzyme B (GrB) ELISPOT as a viable alternative to the (51)Cr-release assay for measuring cytotoxic activity of innate immune effector cells. We strategically selected the GrB ELISPOT assay because GrB is a hallmark effector molecule of cell-mediated destruction...

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Pubblicato in:J Transl Med
Autori principali: Shafer-Weaver, Kimberly A, Sayers, Thomas, Kuhns, Douglas B, Strobl, Susan L, Burkett, Mark W, Baseler, Michael, Malyguine, Anatoli
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2004
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC522821/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15380049/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1479-5876-2-31
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