Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay

BACKGROUND: This study assessed the Granzyme B (GrB) ELISPOT as a viable alternative to the (51)Cr-release assay for measuring cytotoxic activity of innate immune effector cells. We strategically selected the GrB ELISPOT assay because GrB is a hallmark effector molecule of cell-mediated destruction...

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Detalles Bibliográficos
Main Authors: Shafer-Weaver, Kimberly A, Sayers, Thomas, Kuhns, Douglas B, Strobl, Susan L, Burkett, Mark W, Baseler, Michael, Malyguine, Anatoli
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2004
Assuntos:
Methodology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC522821/
https://ncbi.nlm.nih.gov/pubmed/15380049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-31
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