The Granzyme B ELISPOT assay: an alternative to the (51)Cr-release assay for monitoring cell-mediated cytotoxicity

BACKGROUND: The interferon-γ (IFN-γ) ELISPOT assay is one of the most useful techniques for immunological monitoring of cancer vaccine trials and has gained increased application as a measure of specific T cell activation. However, it does not assess cell-mediated cytotoxicity directly as IFN-γ secr...

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Autors principals: Shafer-Weaver, Kimberly, Sayers, Thomas, Strobl, Susan, Derby, Eric, Ulderich, Tracy, Baseler, Michael, Malyguine, Anatoli
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317386/
https://ncbi.nlm.nih.gov/pubmed/14697097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-1-14
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