Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics

Human mutations in KATNB1 (p80) cause severe congenital cortical malformations, which encompass the clinical features of both microcephaly and lissencephaly. Although p80 plays critical roles during brain development, the underlying mechanisms remain predominately unknown. Here, we demonstrate that...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jin, Mingyue, Pomp, Oz, Shinoda, Tomoyasu, Toba, Shiori, Torisawa, Takayuki, Furuta, Ken’ya, Oiwa, Kazuhiro, Yasunaga, Takuo, Kitagawa, Daiju, Matsumura, Shigeru, Miyata, Takaki, Tan, Thong Teck, Reversade, Bruno, Hirotsune, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228124/
https://ncbi.nlm.nih.gov/pubmed/28079116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39902
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