Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics

Human mutations in KATNB1 (p80) cause severe congenital cortical malformations, which encompass the clinical features of both microcephaly and lissencephaly. Although p80 plays critical roles during brain development, the underlying mechanisms remain predominately unknown. Here, we demonstrate that...

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Pubblicato in:Sci Rep
Autori principali: Jin, Mingyue, Pomp, Oz, Shinoda, Tomoyasu, Toba, Shiori, Torisawa, Takayuki, Furuta, Ken’ya, Oiwa, Kazuhiro, Yasunaga, Takuo, Kitagawa, Daiju, Matsumura, Shigeru, Miyata, Takaki, Tan, Thong Teck, Reversade, Bruno, Hirotsune, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228124/
https://ncbi.nlm.nih.gov/pubmed/28079116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39902
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