Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23

Tumour cells secrete exosomes that are involved in the remodelling of the tumour–stromal environment and promoting malignancy. The mechanisms governing tumour exosome release, however, remain incompletely understood. Here we show that tumour cell exosomes secretion is controlled by pyruvate kinase t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wei, Yao, Wang, Dong, Jin, Fangfang, Bian, Zhen, Li, Limin, Liang, Hongwei, Li, Mingzhen, Shi, Lei, Pan, Chaoyun, Zhu, Dihan, Chen, Xi, Hu, Gang, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228053/
https://ncbi.nlm.nih.gov/pubmed/28067230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14041
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