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Role of Signal Regulatory Protein α in Arsenic Trioxide-induced Promyelocytic Leukemia Cell Apoptosis

Signal regulatory protein α (SIRPα) has been shown to operate as a negative regulator in cancer cell survival. The mechanism underneath such function, however, remains poorly defined. In the present study, we demonstrate that overexpression of SIRPα in acute promyelocytic leukemia (APL) cells result...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pan, Chaoyun, Zhu, Dihan, Zhuo, Jianjiang, Li, Limin, Wang, Dong, Zhang, Chen-Yu, Liu, Yuan, Zen, Ke
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806322/
https://ncbi.nlm.nih.gov/pubmed/27010069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23710
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