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Role of Signal Regulatory Protein α in Arsenic Trioxide-induced Promyelocytic Leukemia Cell Apoptosis

Signal regulatory protein α (SIRPα) has been shown to operate as a negative regulator in cancer cell survival. The mechanism underneath such function, however, remains poorly defined. In the present study, we demonstrate that overexpression of SIRPα in acute promyelocytic leukemia (APL) cells result...

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Foilsithe in:Sci Rep
Main Authors: Pan, Chaoyun, Zhu, Dihan, Zhuo, Jianjiang, Li, Limin, Wang, Dong, Zhang, Chen-Yu, Liu, Yuan, Zen, Ke
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806322/
https://ncbi.nlm.nih.gov/pubmed/27010069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23710
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