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Argonaute 2 Complexes Selectively Protect the Circulating MicroRNAs in Cell-Secreted Microvesicles

Cell-secreted miRNAs are highly stable and can serve as biomarkers for various diseases and signaling molecules in intercellular communication. The mechanism underlying the stability of circulating miRNAs, however, remains incompletely understood. Here we show that Argonaute 2 (Ago2) complexes and m...

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Hlavní autoři: Li, Limin, Zhu, Dihan, Huang, Lei, Zhang, Jing, Bian, Zhen, Chen, Xi, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471944/
https://ncbi.nlm.nih.gov/pubmed/23077538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046957
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