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Argonaute 2 Complexes Selectively Protect the Circulating MicroRNAs in Cell-Secreted Microvesicles

Cell-secreted miRNAs are highly stable and can serve as biomarkers for various diseases and signaling molecules in intercellular communication. The mechanism underlying the stability of circulating miRNAs, however, remains incompletely understood. Here we show that Argonaute 2 (Ago2) complexes and m...

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Main Authors: Li, Limin, Zhu, Dihan, Huang, Lei, Zhang, Jing, Bian, Zhen, Chen, Xi, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471944/
https://ncbi.nlm.nih.gov/pubmed/23077538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046957
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