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Argonaute 2 Complexes Selectively Protect the Circulating MicroRNAs in Cell-Secreted Microvesicles

Cell-secreted miRNAs are highly stable and can serve as biomarkers for various diseases and signaling molecules in intercellular communication. The mechanism underlying the stability of circulating miRNAs, however, remains incompletely understood. Here we show that Argonaute 2 (Ago2) complexes and m...

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Detalles Bibliográficos
Main Authors: Li, Limin, Zhu, Dihan, Huang, Lei, Zhang, Jing, Bian, Zhen, Chen, Xi, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471944/
https://ncbi.nlm.nih.gov/pubmed/23077538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046957
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