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Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases

Neurodegenerative diseases (NDs) often involve the formation of abnormal and toxic protein aggregates, which are thought to be the primary factor in ND occurrence and progression. Aged neurons exhibit marked increases in aggregated protein levels, which can lead to increased cell death in specific b...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Im, Eunju, Chung, Kwang Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227139/
https://ncbi.nlm.nih.gov/pubmed/27312603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.9.094
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