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ASK1 Negatively Regulates the 26 S Proteasome
The 26 S proteasome, composed of the 20 S core and 19 S regulatory particle, plays a central role in ubiquitin-dependent proteolysis. Disruption of this process contributes to the pathogenesis of the various diseases; however, the mechanisms underlying the regulation of 26 S proteasome activity rema...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978573/ https://ncbi.nlm.nih.gov/pubmed/20843792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133777 |
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