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ASK1 Negatively Regulates the 26 S Proteasome

The 26 S proteasome, composed of the 20 S core and 19 S regulatory particle, plays a central role in ubiquitin-dependent proteolysis. Disruption of this process contributes to the pathogenesis of the various diseases; however, the mechanisms underlying the regulation of 26 S proteasome activity rema...

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Detalhes bibliográficos
Main Authors: Um, Ji Won, Im, Eunju, Park, Joongkyu, Oh, Yohan, Min, Boram, Lee, Hyun Jung, Yoon, Jong Bok, Chung, Kwang Chul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978573/
https://ncbi.nlm.nih.gov/pubmed/20843792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133777
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