Macrophage polarization in response to epigenetic modifiers during infection and inflammation

Macrophages are a heterogeneous population of phagocytic cells present in all tissues. Recently, several drugs that target the epigenetic machinery have emerged as attractive molecules for treating infection and inflammation by modulating macrophages. Treatment of lipopolysaccharide (LPS)-challenged...

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Udgivet i:Drug Discov Today
Main Authors: Patel, Urmi, Rajasingh, Sheeja, Samanta, Saheli, Cao, Thuy, Dawn, Buddhadeb, Rajasingh, Johnson
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226865/
https://ncbi.nlm.nih.gov/pubmed/27554801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.08.006
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