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Macrophage polarization in response to epigenetic modifiers during infection and inflammation

Macrophages are a heterogeneous population of phagocytic cells present in all tissues. Recently, several drugs that target the epigenetic machinery have emerged as attractive molecules for treating infection and inflammation by modulating macrophages. Treatment of lipopolysaccharide (LPS)-challenged...

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Détails bibliographiques
Publié dans:Drug Discov Today
Auteurs principaux: Patel, Urmi, Rajasingh, Sheeja, Samanta, Saheli, Cao, Thuy, Dawn, Buddhadeb, Rajasingh, Johnson
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226865/
https://ncbi.nlm.nih.gov/pubmed/27554801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.08.006
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