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Macrophage polarization in response to epigenetic modifiers during infection and inflammation

Macrophages are a heterogeneous population of phagocytic cells present in all tissues. Recently, several drugs that target the epigenetic machinery have emerged as attractive molecules for treating infection and inflammation by modulating macrophages. Treatment of lipopolysaccharide (LPS)-challenged...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Discov Today
Hauptverfasser: Patel, Urmi, Rajasingh, Sheeja, Samanta, Saheli, Cao, Thuy, Dawn, Buddhadeb, Rajasingh, Johnson
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226865/
https://ncbi.nlm.nih.gov/pubmed/27554801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2016.08.006
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