Bad to the Bone: On In Vitro and Ex Vivo Microbial Biofilm Ability to Directly Destroy Colonized Bone Surfaces without Participation of Host Immunity or Osteoclastogenesis

Bone infections are a significant public health burden associated with morbidity and mortality in patients. Microbial biofilm pathogens are the causative agents in chronic osteomyelitis. Research on the pathogenesis of osteomyelitis has focused on indirect bone destruction by host immune cells and c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Junka, Adam, Szymczyk, Patrycja, Ziółkowski, Grzegorz, Karuga-Kuzniewska, Ewa, Smutnicka, Danuta, Bil-Lula, Iwona, Bartoszewicz, Marzenna, Mahabady, Susan, Sedghizadeh, Parish Paymon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226730/
https://ncbi.nlm.nih.gov/pubmed/28076372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169565
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