Bad to the Bone: On In Vitro and Ex Vivo Microbial Biofilm Ability to Directly Destroy Colonized Bone Surfaces without Participation of Host Immunity or Osteoclastogenesis

Bone infections are a significant public health burden associated with morbidity and mortality in patients. Microbial biofilm pathogens are the causative agents in chronic osteomyelitis. Research on the pathogenesis of osteomyelitis has focused on indirect bone destruction by host immune cells and c...

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Vydáno v:PLoS One
Hlavní autoři: Junka, Adam, Szymczyk, Patrycja, Ziółkowski, Grzegorz, Karuga-Kuzniewska, Ewa, Smutnicka, Danuta, Bil-Lula, Iwona, Bartoszewicz, Marzenna, Mahabady, Susan, Sedghizadeh, Parish Paymon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226730/
https://ncbi.nlm.nih.gov/pubmed/28076372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169565
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