Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ebola (EBOV) and Marburg (MARV) viruses are members of the Filoviridae family which cause outbreaks of hemorrhagic fever. The filovirus VP40 matrix protein is essential for virus assembly and budding, and its PPxY L-domain motif interacts with WW-domains of specific host proteins, such as Nedd4 and...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Liang, Jingjing, Sagum, Cari A., Bedford, Mark T., Sidhu, Sachdev S., Sudol, Marius, Han, Ziying, Harty, Ronald N.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226679/
https://ncbi.nlm.nih.gov/pubmed/28076420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006132
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