Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ebola (EBOV) and Marburg (MARV) viruses are members of the Filoviridae family which cause outbreaks of hemorrhagic fever. The filovirus VP40 matrix protein is essential for virus assembly and budding, and its PPxY L-domain motif interacts with WW-domains of specific host proteins, such as Nedd4 and...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Liang, Jingjing, Sagum, Cari A., Bedford, Mark T., Sidhu, Sachdev S., Sudol, Marius, Han, Ziying, Harty, Ronald N.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226679/
https://ncbi.nlm.nih.gov/pubmed/28076420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006132
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