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Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ebola (EBOV) and Marburg (MARV) viruses are members of the Filoviridae family which cause outbreaks of hemorrhagic fever. The filovirus VP40 matrix protein is essential for virus assembly and budding, and its PPxY L-domain motif interacts with WW-domains of specific host proteins, such as Nedd4 and...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Liang, Jingjing, Sagum, Cari A., Bedford, Mark T., Sidhu, Sachdev S., Sudol, Marius, Han, Ziying, Harty, Ronald N.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226679/
https://ncbi.nlm.nih.gov/pubmed/28076420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006132
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