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miR-29c contribute to glioma cells temozolomide sensitivity by targeting O(6)-methylguanine-DNA methyltransferases indirectly
Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy. However growing resistance to TMZ remains a major challenge to clinicians. The DNA repair protein O(6)-methylguanine-DNA methytransferase (MGMT) plays critical roles in TMZ resistance. Promoter methylation can inhi...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226579/ https://ncbi.nlm.nih.gov/pubmed/27384876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10357 |
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