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Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC cells. Here we found that treatment of high-grade...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Amantini, Consuelo, Morelli, Maria Beatrice, Nabissi, Massimo, Cardinali, Claudio, Santoni, Matteo, Gismondi, Angela, Santoni, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226576/
https://ncbi.nlm.nih.gov/pubmed/27367032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10326
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