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Telomere recognition and assembly mechanism of mammalian shelterin

Shelterin is a six-subunit protein complex that plays crucial roles in telomere length regulation, protection and maintenance. Although several shelterin subunits have been studied in vitro, the biochemical properties of the fully assembled shelterin complex are not well defined. Here we characteriz...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Erdel, Fabian, Kratz, Katja, Willcox, Smaranda, Griffith, Jack D., Greene, Eric C., de Lange, Titia
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225662/
https://ncbi.nlm.nih.gov/pubmed/28052260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.005
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