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A fission yeast cell-based system for multidrug resistant HIV-1 proteases
BACKGROUND: HIV-1 protease (PR) is an essential enzyme for viral production. Thus, PR inhibitors (PIs) are the most effective class of anti-HIV drugs. However, the main challenge to the successful use of PI drugs in patient treatment is the emergence of multidrug resistant PRs ((mdr)PRs). This study...
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| Publicado no: | Cell Biosci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225522/ https://ncbi.nlm.nih.gov/pubmed/28096973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0131-5 |
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