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Single-Agent and Fixed-Dose Combination HIV-1 Protease Inhibitor Drugs in Fission Yeast (Schizosaccharomyces pombe)

Successful combination antiretroviral therapies (cART) eliminate active replicating HIV-1, slow down disease progression, and prolong lives. However, cART effectiveness could be compromised by the emergence of viral multidrug resistance, suggesting the need for new drug discoveries. The objective of...

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Détails bibliographiques
Publié dans:Pathogens
Auteurs principaux: Zhang, Jiantao, Vernon, Kasey, Li, Qi, Benko, Zsigmond, Amoroso, Anthony, Nasr, Mohamed, Zhao, Richard Y.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8308830/
https://ncbi.nlm.nih.gov/pubmed/34202872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10070804
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