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Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion

To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene targeting. When...

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Bibliografski detalji
Izdano u:mBio
Glavni autori: van Wijk, Xander M., Döhrmann, Simon, Hallström, Björn M., Li, Shangzhong, Voldborg, Bjørn G., Meng, Brandon X., McKee, Karen K., van Kuppevelt, Toin H., Yurchenco, Peter D., Palsson, Bernhard O., Lewis, Nathan E., Nizet, Victor, Esko, Jeffrey D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225314/
https://ncbi.nlm.nih.gov/pubmed/28074024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02128-16
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