Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion

To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene targeting. When...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: van Wijk, Xander M., Döhrmann, Simon, Hallström, Björn M., Li, Shangzhong, Voldborg, Bjørn G., Meng, Brandon X., McKee, Karen K., van Kuppevelt, Toin H., Yurchenco, Peter D., Palsson, Bernhard O., Lewis, Nathan E., Nizet, Victor, Esko, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225314/
https://ncbi.nlm.nih.gov/pubmed/28074024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02128-16
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