HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation

Mounting evidence implicates antiretroviral (ARV) drugs as potential contributors to the persistence and evolution of clinical and pathological presentation of HIV-associated neurocognitive disorders in the post-ARV era. Based on their ability to induce endoplasmic reticulum (ER) stress in various c...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Gannon, Patrick J., Akay-Espinoza, Cagla, Yee, Alan C., Briand, Lisa A., Erickson, Michelle A., Gelman, Benjamin B., Gao, Yan, Haughey, Norman J., Zink, M. Christine, Clements, Janice E., Kim, Nicholas S., Van De Walle, Gabriel, Jensen, Brigid K., Vassar, Robert, Pierce, R. Christopher, Gill, Alexander J., Kolson, Dennis L., Diehl, J. Alan, Mankowski, Joseph L., Jordan-Sciutto, Kelly L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225305/
https://ncbi.nlm.nih.gov/pubmed/27993242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.09.006
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