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A simplified and scalable synthesis of artesunate
ABSTRACT: An efficient and economically viable approach for the large-scale conversion of artemisinin into the antimalarial frontline drug artesunate was developed. This advanced synthesis includes an NaBH(4)-induced reduction, followed by an esterification with succinic anhydride under basic condit...
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| Yayımlandı: | Monatsh Chem |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Vienna
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225229/ https://ncbi.nlm.nih.gov/pubmed/28127092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1865-9 |
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