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Improved simplicity and practicability in copper-catalyzed alkynylation of tetrahydroisoquinoline

ABSTRACT: Alkynylation reactions of N-protected tetrahydroisoquinolines have been performed using several different protocols of cross dehydrogenative coupling. Initially, a CuCl-catalyzed method was investigated, which worked well with three different N-protecting groups, namely phenyl, PMP, and be...

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Detalhes bibliográficos
Publicado no:Monatsh Chem
Main Authors: Gröll, Birgit, Schaaf, Patricia, Schnürch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225217/
https://ncbi.nlm.nih.gov/pubmed/28127095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1877-5
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