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Direct Functionalization of (Un)protected Tetrahydroisoquinoline and Isochroman under Iron and Copper Catalysis: Two Metals, Two Mechanisms

[Image: see text] A highly facile, straightforward synthesis of 1-(3-indolyl)-tetrahydroisoquinolines was developed using either simple copper or iron catalysts. N-protected and unprotected tetrahydroisoquinolines (THIQ) could be used as starting materials. Extension of the substrate scope of the pr...

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Detalhes bibliográficos
Main Authors: Ghobrial, Michael, Schnürch, Michael, Mihovilovic, Marko D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226323/
https://ncbi.nlm.nih.gov/pubmed/21902275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo201511d
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