Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Identification of neurotoxic drugs and environmental chemicals is an important challenge. However, only few tools to address this topic are available. The aim of this study was to develop a neurotoxicity/developmental neurotoxicity (DNT) test system, using the pluripotent mouse embryonic stem cell l...

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Dettagli Bibliografici
Pubblicato in:Arch Toxicol
Autori principali: Colaianna, Marilena, Ilmjärv, Sten, Peterson, Hedi, Kern, Ilse, Julien, Stephanie, Baquié, Mathurin, Pallocca, Giorgia, Bosgra, Sieto, Sachinidis, Agapios, Hengstler, Jan G., Leist, Marcel, Krause, Karl-Heinz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
Soggetti:
In vitro Systems
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225183/
https://ncbi.nlm.nih.gov/pubmed/27015953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1690-2
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