Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Identification of neurotoxic drugs and environmental chemicals is an important challenge. However, only few tools to address this topic are available. The aim of this study was to develop a neurotoxicity/developmental neurotoxicity (DNT) test system, using the pluripotent mouse embryonic stem cell l...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Colaianna, Marilena, Ilmjärv, Sten, Peterson, Hedi, Kern, Ilse, Julien, Stephanie, Baquié, Mathurin, Pallocca, Giorgia, Bosgra, Sieto, Sachinidis, Agapios, Hengstler, Jan G., Leist, Marcel, Krause, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
In vitro Systems
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225183/
https://ncbi.nlm.nih.gov/pubmed/27015953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1690-2
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