Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma

BACKGROUND: The lack of a general clinic-relevant model for human cancer is a major impediment to the acceleration of novel therapeutic approaches for clinical use. We propose to establish and characterize primary human hepatocellular carcinoma (HCC) xenografts that can be used to evaluate the cytot...

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Pubblicato in:Front Immunol
Autori principali: Jiang, Zhiwu, Jiang, Xiaofeng, Chen, Suimin, Lai, Yunxin, Wei, Xinru, Li, Baiheng, Lin, Simiao, Wang, Suna, Wu, Qiting, Liang, Qiubin, Liu, Qifa, Peng, Muyun, Yu, Fenglei, Weng, Jianyu, Du, Xin, Pei, Duanqing, Liu, Pentao, Yao, Yao, Xue, Ping, Li, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225101/
https://ncbi.nlm.nih.gov/pubmed/28123387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00690
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