CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg(−/−) Mice Results in Severe Immunodeficiency

Immunodeficient mice engrafted with either normal or cancerous human cells are widely used in basic and translational research. In particular, NOD/SCID/IL2rg(−/−) mice can support the growth of various types of human cancer cells. However, the hairs of these mice interfere with the observation and i...

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Publicado no:Sci Rep
Main Authors: Wei, Xinru, Lai, Yunxin, Li, Baiheng, Qin, Le, Xu, Youdi, Lin, Simiao, Wang, Suna, Wu, Qiting, Liang, Qiubin, Huang, Guohua, Deng, Qiuhua, Liu, Pentao, Wu, Donghai, Lai, Liangxue, Yao, Yao, Li, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552779/
https://ncbi.nlm.nih.gov/pubmed/28798321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08337-8
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