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Moderate endoplasmic reticulum stress activates a PERK and p38-dependent apoptosis

The endoplasmic reticulum (ER) has the ability to signal organelle dysfunction via a complex signaling network known as the unfolded protein response (UPR). In this work, hamster fibroblast cells exhibiting moderate levels of ER stress were compared to those exhibiting severe ER stress. Inhibition o...

詳細記述

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書誌詳細
出版年:Cell Stress Chaperones
主要な著者: Lumley, Emily C., Osborn, Acadia R., Scott, Jessica E., Scholl, Amanda G., Mercado, Vicki, McMahan, Young T., Coffman, Zachary G., Brewster, Jay L.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Netherlands 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225058/
https://ncbi.nlm.nih.gov/pubmed/27761878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0740-2
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