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Adenosine A2a receptor signals inhibit germinal center T follicular helper cell differentiation during the primary response to vaccination

Adenosine A2a receptor (A2aR) signaling acts as a barrier to autoimmunity by promoting anergy, inducing regulatory T cells (Tregs), and inhibiting effector T cells. However, in vivo effects of A2aR signaling on polyclonal CD4 T cells during a primary response to foreign antigen has yet to be determi...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Schmiel, Shirdi E., Yang, Jessica A., Jenkins, Marc K., Mueller, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225048/
https://ncbi.nlm.nih.gov/pubmed/27986907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601686
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