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Cutting Edge: Helminth coinfection blocks effector differentiation of CD8 T cells through alternate host Th2- and IL-10-mediated responses

Concurrent helminth infection potently inhibits T cell immunity; however, whether helminths prevent T cell priming or skew clonal recruitment and effector differentiation is not known. Using coinfection with two natural mouse pathogens, Heligsomosoides polygyrus and Toxoplasma gondii to investigate...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Marple, Andrew, Wu, Wenhui, Shah, Suhagi, Zhao, Yanlin, Du, Peicheng, Gause, William C., Yap, George S.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225035/
https://ncbi.nlm.nih.gov/pubmed/27956529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601741
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