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Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation
BACKGROUND: Dabigatran etexilate is a prodrug whose absorption is opposed by intestinal P-glycoprotein and which is converted by carboxylesterase to its active form, dabigatran. Unlike other statins, simvastatin and lovastatin are potent inhibitors of P-glycoprotein and carboxylesterase, and might e...
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| 出版年: | CMAJ |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Joule Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224945/ https://ncbi.nlm.nih.gov/pubmed/28246253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.160303 |
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