Trimethoprim–sulfamethoxazole and risk of sudden death among patients taking spironolactone

BACKGROUND: Trimethoprim–sulfamethoxazole increases the risk of hyperkalemia when used with spironolactone. We examined whether this drug combination is associated with an increased risk of sudden death, a consequence of severe hyperkalemia. METHODS: We conducted a population-based nested case–contr...

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Detalles Bibliográficos
Publicado en:CMAJ
Main Authors: Antoniou, Tony, Hollands, Simon, Macdonald, Erin M., Gomes, Tara, Mamdani, Muhammad M., Juurlink, David N.
Formato: Artigo
Idioma:Inglês
Publicado: 8872147 Canada Inc. 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347789/
https://ncbi.nlm.nih.gov/pubmed/25646289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.140816
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