The role of FilGAP, a Rac‐specific Rho‐GTPase‐activating protein, in tumor progression and behavior of astrocytomas

FilGAP, a Rac‐specific Rho‐GTPase‐activating protein (GAP), acts as a mediator of Rho/ROCK‐dependent amoeboid movement, and its knockdown results in Rac‐driven mesenchymal morphology. Herein, we focused on the possible roles of FilGAP expression in astrocytomas. In clinical samples, FilGAP expressio...

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Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Hara, Atsuko, Hashimura, Miki, Tsutsumi, Koji, Akiya, Masashi, Inukai, Madoka, Ohta, Yasutaka, Saegusa, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Clinical Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224849/
https://ncbi.nlm.nih.gov/pubmed/27790861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.937
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