ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation

Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Here we examined the functional role of the ALK gene in glioblastomas (GBMs). In clinical samples of GBMs, high ALK expression without gene rearrangements...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Chiba, Risako, Akiya, Masashi, Hashimura, Miki, Oguri, Yasuko, Inukai, Madoka, Hara, Atsuko, Saegusa, Makoto
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570309/
https://ncbi.nlm.nih.gov/pubmed/28837676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183516
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