ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation

Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Here we examined the functional role of the ALK gene in glioblastomas (GBMs). In clinical samples of GBMs, high ALK expression without gene rearrangements...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Chiba, Risako, Akiya, Masashi, Hashimura, Miki, Oguri, Yasuko, Inukai, Madoka, Hara, Atsuko, Saegusa, Makoto
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570309/
https://ncbi.nlm.nih.gov/pubmed/28837676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183516
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