ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation

Anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase, is essentially and transiently expressed in the developing nervous system. Here we examined the functional role of the ALK gene in glioblastomas (GBMs). In clinical samples of GBMs, high ALK expression without gene rearrangements...

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Publicat a:PLoS One
Autors principals: Chiba, Risako, Akiya, Masashi, Hashimura, Miki, Oguri, Yasuko, Inukai, Madoka, Hara, Atsuko, Saegusa, Makoto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570309/
https://ncbi.nlm.nih.gov/pubmed/28837676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183516
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