FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma

FilGAP, a Rho GTPase-activating protein (GAP), acts as a mediator of Rho/ROCK (Rho-associated protein kinase)-dependent amoeboid movement, and its knockdown results in Rac-driven mesenchymal morphology. Herein, we focus on the possible roles of FilGAP expression in normal and malignant lymphocytes....

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Nishi, Tatsuya, Takahashi, Hiroyuki, Hashimura, Miki, Yoshida, Tsutomu, Ohta, Yasutaka, Saegusa, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472203/
https://ncbi.nlm.nih.gov/pubmed/25641953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.423
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