טוען...

Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia

Data integration stands to improve interpretation of RNAi screens which, as a result of off-target effects, typically yield numerous gene hits of which only a few validate. These off-target effects can result from seed matches to unintended gene targets (reagent-based) or cellular pathways, which ca...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Integr Biol (Camb)
Main Authors: Wilson, Jennifer L., Dalin, Simona, Gosline, Sara, Hemann, Michael, Fraenkel, Ernest, Lauffenburger, Douglas A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Royal Society of Chemistry 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224708/
https://ncbi.nlm.nih.gov/pubmed/27315426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00040a
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!