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Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO
Podosomes represent a class of integrin-mediated cell-matrix adhesions formed by migrating and matrix-degrading cells. We demonstrate that in macrophage-like THP1 cells and fibroblasts stimulated to produce podosomes, down-regulation of the G-protein ARF1 or the ARF1 guanine nucleotide exchange fact...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223603/ https://ncbi.nlm.nih.gov/pubmed/28007915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605104 |
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