Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity.

The infection of human cells by laboratory strains of human immunodeficiency virus type 1 (HIV-1) can be blocked readily in vitro by recombinant soluble CD4 and CD4-immunoglobulin hybrid molecules. In contrast, infection by primary isolates of HIV-1 is much less sensitive to blocking in vitro by sol...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ashkenazi, A, Smith, D H, Marsters, S A, Riddle, L, Gregory, T J, Ho, D D, Capon, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7056
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