Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity.

The infection of human cells by laboratory strains of human immunodeficiency virus type 1 (HIV-1) can be blocked readily in vitro by recombinant soluble CD4 and CD4-immunoglobulin hybrid molecules. In contrast, infection by primary isolates of HIV-1 is much less sensitive to blocking in vitro by sol...

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Bibliografiske detaljer
Main Authors: Ashkenazi, A, Smith, D H, Marsters, S A, Riddle, L, Gregory, T J, Ho, D D, Capon, D J
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52232/
https://ncbi.nlm.nih.gov/pubmed/1871120
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