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IK acts as an immunoregulator of inflammatory arthritis by suppressing T(H)17 cell differentiation and macrophage activation
Pathogenic T helper cells (T(H)) and macrophages have been implicated in the development of rheumatoid arthritis (RA), which can lead to severe synovial inflammation and bone destruction. A range of therapies have been widely used for RA, including specific monoclonal antibodies and chemical inhibit...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223115/ https://ncbi.nlm.nih.gov/pubmed/28071693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40280 |
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