IK acts as an immunoregulator of inflammatory arthritis by suppressing T(H)17 cell differentiation and macrophage activation

Pathogenic T helper cells (T(H)) and macrophages have been implicated in the development of rheumatoid arthritis (RA), which can lead to severe synovial inflammation and bone destruction. A range of therapies have been widely used for RA, including specific monoclonal antibodies and chemical inhibit...

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Vydáno v:Sci Rep
Hlavní autoři: Park, Hye-Lim, Lee, Sang-Myeong, Min, Jun-Ki, Moon, Su-Jin, Kim, Inki, Kang, Kyung-Won, Park, Sooho, Choi, SeulGi, Jung, Ha-Na, Lee, Dong-Hee, Nam, Jae-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223115/
https://ncbi.nlm.nih.gov/pubmed/28071693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40280
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